Colorectal cancer is now the leading cause of cancer death in people under 50, climbing from fifth place in the 1990s. Following James Van Der Beek's death at 48, Dr. Akerman explains why screening at 45 is critical and compares colonoscopy to newer blood and stool tests. While Cologuard and Shield offer convenience, colonoscopy remains the gold standard because it prevents cancer by removing polyps. Learn when you should get screened, especially if you have a family history